CMSA Charlotte Metro was originated in 1997 as a division of the Greensboro, North Carolina Chapter. In 2003 case managers from various backgrounds began meeting to reorganize the chapter and to build membership. In January 2004 it was incorporated as an independent chapter. CMSA Charlotte Metro held its first regional conference in 2005 "Sail the Calm Seas of Case Management." The membership is made up of nurses and social workers from varied backgrounds to include workers compensation, hospital, and insurance case managers, as well as members that provide case management related services and products.